The versatility of a CNC machine can be somewhat daunting. The fact that it is completely up to the user to enter the correct coordinate values to prevent the machine from crashing is a stressful reality. However, this is exactly the situation for every CNC operator in every manufacturing shop out there. The fact that catastrophic crashes are so rare is only a result of good methods and modern software. The problem is basically 3-parts: the machine needs to know what to do, where to do it, and with what tools.
Step 1 - Programming
Modern CAM software, like Fusion 360, allows point and click toolpath generation of everything from 2-½ D to full 5-axis operations. With additional capabilities like process simulation and crash detection, the CNC programmer can have high confidence in the resulting gcode.